Few specimens of this species have been collected and the localities where it was found are threatened by deforestation and fire.

It is known from the Campinarana vegetation in Manaus (Amazonas, Brazil) and dry evergreen forest and Dicymbe-dominated fores in Pakaraima Mountains (Guyana).

Amanita campinaranae was described by Bas in 1978 from specimens collected in Amazonas, only in 2002 were collected again three specimens in Guyana.

“Terrestrial in Campinarana vegetation under Leguminosae and Sapotaceae in Amazonas; ectotrophic mycorrhiza” (Bas, 1978). Terrestrial in sandy soil of Dycimbe-dominanted forest (Henkel, 2012).

In Guyana A. campinarana was collected in a site lies within a National Park area protected by government. In Brazil due to the preparation of agricultural area, illegal logging, ubanization and mining, Amazon has been deforested and burned. According to the Amazon Monitoring Program of INPE between 2018 and 2019 there was a substantial increase. Approximately 17% of the original Amazon vegetation has already been cleared.

Resume and intensify campaigns to prevent burning; intensify combating fires; increase inspection and monitoring of deforestation. Furthermore, the protection of sites and consevations action are essential for the preservation of treathned areas.

Due to the disjunct distribution of the taxon more sampling is required.